Title

Aerobic Exercise Training Increases Circulating Insulin-Like Growth Factor Binding Protein-1 Concentration, but does not Attenuate the Reduction in Circulating Insulin-Like Growth Factor Binding Protein-1 After a High-Fat Meal

Document Type

Article

Publication Date

2012

Department

Health Sciences

Abstract

Insulin-like growth factor binding protein-1 (IGFBP-1) has metabolic effects throughout the body, and its expression is regulated in part by insulin. High circulating IGFBP-1 concentrations are inversely correlated with cardiometabolic diseases. With this study, we identified increases in IGFBP-1 concentrations after exercise training may be one mechanism by which exercise reduces risk for cardiometabolic diseases in older adults.

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