Oxidative Species Trigger the Activity of G-Protein Coupled Receptor FSHR-1 During Infection

Jennifer A. Giannini, Gettysburg College

Description

In C. elegans, detoxification genes that either counteract reactive oxygen species (ROS) originating from a pathogen or prevent self-harm from host-produced ROS are induced. Determining the role of G-protein coupled receptor FSHR-1 in the induction of these detoxification genes will help elucidate how FSHR-1 functions in the innate immune response of C. elegans.

 
Apr 29th, 4:30 PM Apr 29th, 6:15 PM

Oxidative Species Trigger the Activity of G-Protein Coupled Receptor FSHR-1 During Infection

CUB Ballroom

In C. elegans, detoxification genes that either counteract reactive oxygen species (ROS) originating from a pathogen or prevent self-harm from host-produced ROS are induced. Determining the role of G-protein coupled receptor FSHR-1 in the induction of these detoxification genes will help elucidate how FSHR-1 functions in the innate immune response of C. elegans.