Document Type
Article
Publication Date
9-2013
Department 1
Health Sciences
Abstract
Both hyponatremia and osteopenia separately have been well documented in endurance athletes. Although bone has been shown to act as a “sodium reservoir” to buffer severe plasma sodium derangements in animals, recent data have suggested a similar function in humans. We aimed to explore if acute changes in bone mineral content were associated with changes in plasma sodium concentration in runners participating in a 161 km mountain footrace. Eighteen runners were recruited. Runners were tested immediately pre- and post-race for the following main outcome measures: bone mineral content (BMC) and density (BMD) via dual-energy X-ray absorptiometry (DEXA); plasma sodium concentration ([Na+]p), plasma arginine vasopressin ([AVP]p), serum aldosterone concentration ([aldosterone]s), and total sodium intake. Six subjects finished the race in a mean time of 27.0±2.3 h. All subjects started and finished the race with [Na+]p within the normal range (137.7±2.3 and 136.7±1.6 mEq/l, pre- and post-race, respectively). Positive correlations were noted between change (Δ; post-race minus pre-race) in total BMC (grams) and [Na+]p (mEq/l) (r=0.99; p
Copyright Note
This is the publisher's version of the work. This publication appears in Gettysburg College's institutional repository by permission of the copyright owner for personal use, not for redistribution.
DOI
10.1055/s-0033-1347263
Recommended Citation
Hew-Butler, T., Kristin J. Stuempfle, Martin D. Hoffman. "Bone: Acute Buffer of Plasma Sodium during Exhaustive Exercise?" Hormone and Metabolic Research 45.10 (September 2013), 697-700.
Required Publisher's Statement
Original version is available from the publisher at: https://www.thieme-connect.com/DOI/DOI?10.1055/s-0033-1347263