Document Type
Article
Publication Date
2-2007
Department 1
Physics
Abstract
Measurements of the global conformation of macromolecules can be carried out using small-angle X-ray scattering (SAXS). Glass focusing capillaries, manufactured at the Cornell High Energy Synchrotron Source (CHESS), have been successfully employed for SAXS measurements on the heme protein cytochrome c. These capillaries provide high X-ray flux into a spot size of tens of micrometres, permitting short exposures of small-volume samples. Such a capability is ideal for use in conjunction with microfluidic mixers, where time resolution may be determined by beam size and sample volumes are kept small to facilitate mixing and conserve material.
Copyright Note
This is the publisher's version of the work. This publication appears in Gettysburg College's institutional repository by permission of the copyright owner for personal use, not for redistribution.
Recommended Citation
Lamb J, Cornaby S, Pollack L, et al. Focusing capillary optics for use in solution small-angle X-ray scattering. Journal Of Applied Crystallography. February 2007;40(1):193-195. http://dx.doi.org/10.1107/S0021889806044505
Required Publisher's Statement
© 2007 International Union of Crystallography
Included in
Atomic, Molecular and Optical Physics Commons, Biological and Chemical Physics Commons, Other Physics Commons