Class Year


Document Type

Student Research Paper

Date of Creation

Fall 2022

Department 1

Health Sciences


This paper is a literature review on the subject Age-Related Macular Degeneration (AMD) with a focus on its etiology, pathophysiology, clinical features, diagnosis, treatment, and prevention. AMD is the leading cause of severe and irreversible central vision loss in in individuals over the age of 55. There are two subtypes of AMD referred to as dry and wet respectively. The etiology of this disease is multifactorial and complex, with no hallmark of disease definitively identified. The distinct pathophysiological features differing in dry and wet AMD are explored in this review as well as its diagnosis and treatment. This disease is primarily untreatable, other than stabilizing wet AMD. Although untreatable there are methods of slowing the progression of AMD. These methods are also explored in this review. The final portion of this paper features a “Patient Focus” section in which the disease is humanized via an interview with an Optometrist who regular treats patients with AMD.


Written for HS 376: Pathophysiology of Disease

Included in

Eye Diseases Commons