Class Year


Document Type

Student Research Paper

Date of Creation

Spring 2022

Department 1

Health Sciences


This paper is a review of recent research on the subject of exercise-associated hyponatremia. Hyponatremia is notoriously difficult to diagnose and to treat due to its general symptoms and required specificity in diagnosis in order to assign appropriate treatment. If left untreated, Hyponatremia can result in the development of complications like cerebral edema, seizures, coma, and sometimes death. The pathogenesis of hyponatremia includes multiple proposed mechanisms, including overconsumption of hypotonic fluids, inappropriate release of antidiuretic hormone, inefficiency of fluid filtration by the kidneys, redirection of fluid into intestinal lumen, and activation of the renin-angiotensin-aldosterone system. Signs and symptoms of hyponatremia typically consist of dizziness, fatigue, irritability, generalized weakness, headache, nausea, and decreased urine output. More severe cases can result in presentation of excess thirst, general malaise, fatigue, headache, and vomiting. Timely treatment of hyponatremia is extremely important, and universal diagnosis techniques and treatment methods are still debated.


Written for HS 319: Environmental Physiology